Bing Center publications are made available as a courtesy to our patients & caregivers. Articles are listed by year of publication. The number of articles for each year is shown as (Article Count: x). Clicking the year, and then clicking on the desired article will display the corresponding PDF file from the publication. The Adobe Acrobat viewer is required, and can be obtained (free) from

Featured Impact Articles

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Patients With Waldenström Macroglobulinemia Commonly Present With Iron Deficiency and Those With Severely Depressed Transferrin Saturation Levels Show Response to Parenteral Iron Administration

Anemia often prompts therapy in Waldenström macroglobulinemia (WM), although is not fully explained by bone marrow disease involvement in many patients.  Hepcidin regulates gut absorption and distribution of iron and is elevated and associated with anemia in WM. ...

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MYD88 L265P Somatic Mutation in Waldenström’s Macroglobulinemia

MYD88 L265P is a commonly recurring mutation in patients with Waldenström’s macroglobulinemia that can be useful in differentiating Waldenström’s macroglobulinemia and non-IgM LPL from B-cell disorders that have some of the same features. ...



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Familial Disease Predisposition Impacts Treatment Outcome in Patients With Waldenström Macroglobulinemia

Familial disease is common in Waldenström macroglobulinemia (WM). We examined the impact of familial disease status on treatment outcome in WM and observed that familial disease was associated with inferior outcomes. However patients with familial WM receiving a bortezomib-containing regimen showed improved treatment outcomes vs. those receiving non–bortezomib-containing regimens. Bortezomib-containing regimens may therefore represent a more optimal treatment approach for patients with familial WM. ...

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A new era for Waldenstrom macroglobulinemia: MYD88 L265P

In this issue of Blood, Poulain et al demonstrate the high prevalence of the MYD88 L265P somatic mutation in patients with Waldenstrom macroglobulinemia (WM) and provide insight into its biological relevance in the growth and survival of WM. ...